On semaglutide or tirzepatide, maintaining lean muscle while losing weight is critical — lean chicken breast is one of the best high-protein options at under 200 calories per serving. Broccoli adds sulforaphane, vitamin C, and fiber that support metabolic health during GLP-1 therapy. Avoid fried chicken, breaded cutlets, and heavy cream-based sauces that add unnecessary fat and can worsen GLP-1 nausea and acid reflux. This simple baked combo is a GLP-1 staple.
Preheat oven to 425°F (220°C).
Pat chicken dry and place on one side of a baking sheet.
Toss broccoli florets with olive oil, salt, and pepper on the other side.
Mix Italian seasoning, paprika, salt, and minced garlic.
Rub over chicken.
Bake 20–25 minutes until chicken reaches 165°F internal temperature.
Squeeze lemon juice over both chicken and broccoli before serving.