Coconut water is one of the best hydration bases for Ozempic and Mounjaro users because it naturally replaces potassium and electrolytes lost through reduced food intake, without the added sugars of sports drinks. A single cup provides 600mg of potassium — 13% of the daily requirement — while contributing only 45 calories. Frozen mango delivers a full day's vitamin A and vitamin C, both of which support immune function and skin health during the metabolic changes triggered by semaglutide. Protein powder brings this smoothie to 25g of total protein. Avoid coconut milk, sweetened coconut beverages, or mango juice — these contain 10–20x the calories and sugar of plain coconut water, which directly opposes tirzepatide's blood sugar goals.
Add coconut water and Greek yogurt to blender first.
Add frozen mango chunks and protein powder.
Add ice cubes and lime juice.
Blend on high for 45 seconds until completely smooth.
Taste — add more lime juice if desired.
Pour into a large glass and drink slowly.