Best Easy Turkey Tetrazzini Casserole Recipe

Turkey tetrazzini casserole bakes leftover turkey with pasta in a creamy Parmesan sauce for a satisfying family dinner. This protein-rich dish is the best reason to look forward to Thanksgiving leftovers.

Cook 55 min Difficulty NORMAL 370 kcal
#high protein #diabetic friendly
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Ingredients
Main ingredients
  • cooked turkey breast 3 cups
  • spaghetti 12 oz
  • white mushrooms 8 oz
  • frozen peas 1 cup
  • yellow onion 1 pieces
  • unsalted butter 4 tbsp
  • all-purpose flour 1 cup
  • whole milk 2 cups
  • chicken broth 1 cup
  • Parmesan cheese 1 cup
Seasonings/Sauce
  • kosher salt 1 tsp
  • black pepper 0.5 tsp
  • garlic powder 0.5 tsp
  • Italian seasoning 1 tsp
Nutrition summary
Carbohydrates 38 g 41%
Protein 27 g 29%
Fat 13 g 30%
Serving size 250g
Cooking steps
  1. 1

    Preheat your oven to 375°F (190°C) and grease a 9x13 inch casserole dish for even baking.

  2. 2

    Cook the spaghetti in salted, boiling water until just al dente, about 8 minutes, then drain and set aside.

  3. 3

    Melt butter in a large skillet over medium heat, sauté chopped onion and sliced mushrooms for 5–7 minutes until softened and golden.

  4. 4

    Stir in flour and cook for 1 minute, then gradually whisk in milk and chicken broth, adding cheese and seasoning for a creamy, thick sauce.

  5. 5

    Combine cooked turkey, peas, pasta, and sauce in a large bowl. Toss well, then transfer to the casserole dish. Spread evenly and top with extra Parmesan if desired.

  6. 6

    Bake uncovered for 25–30 minutes, until bubbling and golden brown at the edges. Let it rest for 5 minutes before serving for best texture.

Personalized Q&A
Q. What's the key ingredient in this Turkey Tetrazzini Casserole recipe?
The core ingredient is cooked turkey breast, providing hearty protein and a savory texture that defines the dish. Combined with pasta and a creamy Parmesan sauce, the turkey makes this casserole particularly satisfying and gives it a rich, comforting character.
Q. What is the most important cooking point for this recipe?
The sauce preparation is crucial: after sautéing onions and mushrooms, cook the flour for about one minute before slowly whisking in the milk and broth. Gradually adding liquids and controlling the heat ensures a smooth, creamy sauce without lumps, resulting in a uniform casserole texture.
Q. How can I prevent the casserole from becoming dry or mushy?
Avoid overcooking the pasta—boil it just until al dente, and do not bake the casserole for longer than 30 minutes. Allowing the dish to rest for 5 minutes after baking helps distribute moisture evenly, preserving both tenderness and creaminess.
Q. What is the nutrition profile per serving of Turkey Tetrazzini Casserole?
Each 250g serving contains about 370 kcal, with 38g carbohydrates (41%), 27g protein (29%), and 13g fat (30%). This balance makes it a protein-rich option that is also diabetic-friendly due to moderate carb levels.
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